Iowa City is a city in Johnson County, Iowa, United States. It is the home of the University of Iowa and county seat of Johnson County, at the center of the Iowa City Metropolitan Statistical Area. The U. S. Census Bureau estimated the city's population at 76,290 in 2018, making it the state's fifth-largest city. Iowa City is the county seat of Johnson County. The metropolitan area, which encompasses Johnson and Washington counties, has a population of over 171,000.